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It takes more to lose weight than swearing off escalators or swearing at burgers until they quit hanging out in your mouth. Shape up with this Groupon. Choose Between Two Options $750 for one Smartlipo treatment on a small area (a $2,500 value) $1,499 for one Smartlipo treatment on a large area (a $5,000 value) Click here for a list of valid treatment areas. During the minimally invasive Cynosure Smartlipo treatment, the doctor injects a local anesthetic into the targeted area to numb it. The doctor then makes a small incision in the treatment area and inserts a cannula. A laser fiber inside the cannula then blasts fat cells with energy, causing them to liquefy. If the area is large enough, the doctor will suction out the liquefied fat with a cannula, and if it is small enough, the liquefied